Research

Our research lines are mainly focused on the use of bioactive molecules and nanoparticles in nanomedicine & nanotechnology.

Funded Projects

Active Projects

Nanoestructuras inteligentes contra el melanoma de úvea y el cáncer de páncreas (SAF2017-87305-R)
Funding agency: Ministerio de Economía, Industria y competitividad
Preparación y Escalado de Nanopartículas Modificadas Bajo Estándares Farmacéuticos (IND2017/IND-7809)
Funding agency:Comunidad de Madrid
Nuevas aproximaciones para el tratamiento y detección de melanoma de úvea basadas en nanopartículas de oro funcionalizadas
Funding agency: Asociación Española Contra el CáncerNanomedicine Upscaling for Early
Clinical Phases of Multimodal Cancer Therapy (NoCanTher)
Funding agency: European Commission , H2020, REF: GA 685795
WEB: NoCanTher 
MicroRNA based nanotherapies for the detection and treatment of muscular diseases (NanomiR)

Funding agency: EuronanoMed II (MINECO). REF: PCIN-2016-167
WEB: NanoMir

Past Projects
Diseño y evaluación de agentes terapéuticos y sensores basados en ARNs no codificantes y nanoestructuras (miRGold)
Funding agency: MINECO, REF: SAF2014-56763-R
 
Oligonucleotidos modificados en nanomedicina: deteccion de secuencias de acidos nucleicos e inhibicion de la expresion genica mediante arn interferente
Funding agency: MINECO, REF: SAF2010-15440
Multifunctional Nanotechnology for selective detection and Treatment of cancer (MULTIFUN)
Funding agency: European Commission , FP7, REF: 262943
WEB: Multifun
 
RESEARCH TOPICS
 
1. Nanoparticles in Drug Delivery 

We use different nanostructures to deliver different drugs and nucleic acids for the treatment of different diseases

2. Gene sensors based on nanoparticles.

We are developing gene sensors based on modified oligonucleotides and nanoparticles

3. Modified Magnetic Nanoparticles for the treatment of cancer

NoCanTher

The aim of this collaborative project is to scale-up functionalized nanoparticles for the treatment of pancreatic cancer.

 

Previous project:

MultiFun
The aim of the collaborative project MULTIFUN is to develop functionalized nanoparticles for the detection and treatment of breast and pancreatic cancer.

Seventh Framework Programme grant agreement no. 262943

4. DNA stabilized Silver Nanoclusters

We are working on the preparation and study of fluorescent materials based on silver nanoclusters stabilized with oligonucleotides.

5. Modified Oligonucleotides in RNA interference
We use modified RNA duplexes to study the gene inhibition process known as RNA interference