Publications

Complete list of Dr. Álvaro Somoza’s publications on Google Scholar.

2026

88. T. N. D. Trinh, V. P. Dinh, H. A. Nguyen, N. T. T. Phuong, W. R. Chae, N. Y. Lee, Á. Somoza and K. T. L. Trinh. From Lab to Clinic: Patient‐Based Validation of Microfluidic‐Isothermal Amplification Devices for Early Disease Diagnosis. Advanced Materials Technologies 2026, e71351. doi:10.1002/admt.71351

87. E. Álvarez-Corrales, R. Moreno-Palomares, C. Gómez-Escolar, M. Martínez, U. Moral-Pérez, M. Laguna-Herrero, T. Fuertes, B. S. Estrada, S. Mur, A. de Bonis, M. Leiva, N. Martínez-Martín, Á. Somoza, A. R. Ramiro and V. G. de Yébenes. Targeting of ibrutinib resistance–driving pathways by miR-28 in ABC-DLBCL. Leukemia 2026, 40 (5), 894-905. doi:10.1038/s41375-026-02948-9

86. R. López‐Méndez, N. Lafuente‐Gómez, E. Céspedes, M. Dhanjani, M. París‐Ogáyar, F. José Terán, A. Serrano, J. Camarero, G. Salas, C. Wilhelm, Á. Somoza and A. Espinosa. Tri‐Modal Anticancer Strategies with Doxorubicin‐Loaded Iron Oxide Nanoparticles Integrating Chemo and Magneto‐Photothermal Therapeutic Effects. Advanced NanoBiomed Research 2026, 6 (1), e70084. doi:10.1002/anbr.70084

2025

85. N. Lafuente-Gómez, M. Martínez-Mingo, Z. V. Díaz-Riascos, B. García-Prats, I. de la Iglesia, M. Dhanjani, D. García-Soriano, L. A. Campos, S. Mancilla-Zamora, G. Salas, I. Abasolo and Á. Somoza. Gemcitabine and miRNA34a mimic codelivery with magnetic nanoparticles enhanced anti-tumor effect against pancreatic cancer. Journal of Controlled Release 2025, 383, 113791. doi:10.1016/j.jconrel.2025.113791

84. P. Garrido-García, I. Quirós, P. Milán-Rois, S. Ortega-Gutiérrez, M. Martín-Fontecha, L. A. Campos, Á. Somoza, I. Fernández, T. Rigotti and M. Tortosa. Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as ortho-disubstituted benzene bioisosteres with improved biological activity. Nature Chemistry 2025, 17 (5), 734-745. doi:10.1038/s41557-025-01746-7

83. F. Millozzi, P. Milán-Rois, A. Sett, G. Delli Carpini, M. De Bardi, M. Gisbert-Garzarán, M. Sandonà, C. Rodríguez-Díaz, M. Martínez-Mingo, I. Pardo, F. Esposito, M. T. Viscomi, M. Bouché, O. Parolini, V. Saccone, J.-J. Toulmé, Á. Somoza and D. Palacios. Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle stem cells to promote regeneration of dystrophic muscles. Nature Communications 2025, 16 (1), 577. doi:10.1038/s41467-024-55223-9

82. Z. V. Díaz-Riascos, M. Llaguno-Munive, N. Lafuente-Gómez, Y. Luengo, S. Holmes, J. Volatron, O. Ibarrola, S. Mancilla, F. Sarno, J. J. Aguirre, S. Razafindrakoto, P. Southern, F. J. Terán, A. Keogh, G. Salas, A. Prina-Mello, J. C. Lacal, A. del Pozo, Q. A. Pankhurst, M. Hidalgo, F. Gazeau, Á. Somoza, S. Schwartz and I. Abasolo. Preclinical Development of Magnetic Nanoparticles for Hyperthermia Treatment of Pancreatic Cancer. ACS Applied Materials & Interfaces 2025, 17 (2), 2924-2939. doi:10.1021/acsami.4c16129

2024

81. A. Martín-Asensio, I. Pardo, R. Mesa, D. Pardo, J. P. Fernández-Blázquez, J. C. Martínez-Guil, M. Castellanos, J. J. Hernández, Á. Somoza and I. Rodríguez. Investigating non fluorescence nanoparticle transport in Matrigel-filled microfluidic devices using synchrotron X-ray scattering. Micro and Nano Systems Letters 2024, 12 (1), 22. doi:10.1186/s40486-024-00213-1

80. D. García-Soriano, P. Milán-Rois, N. Lafuente-Gómez, C. Rodríguez-Díaz, C. Navío, Á. Somoza and G. Salas. Multicore iron oxide nanoparticles for magnetic hyperthermia and combination therapy against cancer cells. Journal of Colloid and Interface Science 2024, 670, 73-85. doi:10.1016/j.jcis.2024.05.046

79. L. Gutiérrez-Gálvez, D. García-Fernández, M. D. Barrio, M. Luna, Í. Torres, F. Zamora, C. Navío, P. Milán-Rois, M. Castellanos, M. Abreu, R. Cantón, J. C. Galán, Á. Somoza, R. Miranda, T. García-Mendiola and E. Lorenzo. Free PCR virus detection via few-layer bismuthene and tetrahedral DNA nanostructured assemblies. Talanta 2024, 269, 125405. doi:10.1016/j.talanta.2023.125405

2023

78. N. Lafuente-Gómez, I. de Lázaro, M. Dhanjani, D. García-Soriano, M. C. Sobral, G. Salas, D. J. Mooney and Á. Somoza. Multifunctional magnetic nanoparticles elicit anti-tumor immunity in a mouse melanoma model. Materials Today Bio 2023, 23, 100817. doi:10.1016/j.mtbio.2023.100817

77. C. Escalona-Noguero, H. Alarcón-Iniesta, M. López-Valls, L. P. del Carpio, J. M. Piulats, Á. Somoza and B. Sot. Detection of the Uveal Melanoma-Associated Mutation GNAQ Q209P from Liquid Biopsy Using CRISPR/Cas12a Technology. Analytical Chemistry 2023, 95 (45), 16692-16700. doi:10.1021/acs.analchem.3c03460

76. P. Fernández-Gómez, C. Pérez de la Lastra Aranda, C. Tosat-Bitrián, J. A. Bueso de Barrio, S. Thompson, B. Sot, G. Salas, Á. Somoza, A. Espinosa, M. Castellanos and V. Palomo. Nanomedical research and development in Spain: improving the treatment of diseases from the nanoscale. Frontiers in Bioengineering and Biotechnology 2023, 11, 1191327. doi:10.3389/fbioe.2023.1191327

75. M. Castellanos and Á. Somoza. Emerging clinically tested detection methods for COVID‐19. The FEBS Journal 2023, 290 (12), 3089-3104. doi:10.1111/febs.16469

2022

74. C. Pina-Coronado, Á. Martínez-Sobrino, L. Gutiérrez-Gálvez, R. Del Caño, E. Martínez-Periñán, D. García-Nieto, M. Rodríguez-Peña, M. Luna, P. Milán-Rois, M. Castellanos, M. Abreu, R. Cantón, J. C. Galán, T. Pineda, F. Pariente, Á. Somoza, T. García-Mendiola, R. Miranda and E. Lorenzo. Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures for sensitive and selective SARS-CoV-2 sensing. Sensors and Actuators B: Chemical 2022, 369, 132217. doi:10.1016/j.snb.2022.132217

73. K. Kaci, R. del Caño, M. Luna, P. Milán-Rois, M. Castellanos, M. Abreu, R. Cantón, J. C. Galán, Á. Somoza, R. Miranda, G. González de Rivera, T. García-Mendiola and E. Lorenzo. Paving the way to point of care (POC) devices for SARS-CoV-2 detection. Talanta 2022, 247, 123542. doi:10.1016/j.talanta.2022.123542

72. S. G. Dosil, S. Lopez-Cobo, A. Rodriguez-Galan, I. Fernandez-Delgado, M. Ramirez-Huesca, P. Milan-Rois, M. Castellanos, Á. Somoza, M. J. Gómez, H. T. Reyburn, M. Vales-Gomez, F. Sánchez Madrid and L. Fernandez-Messina. Natural killer (NK) cell-derived extracellular-vesicle shuttled microRNAs control T cell responses. eLife 2022, 11, e76319. doi:10.7554/elife.76319

71. Y. Luengo, Z. V. Díaz-Riascos, D. García-Soriano, F. J. Teran, E. J. Artés-Ibáñez, O. Ibarrola, Á. Somoza, R. Miranda, S. Schwartz, I. Abasolo and G. Salas. Fine Control of In Vivo Magnetic Hyperthermia Using Iron Oxide Nanoparticles with Different Coatings and Degree of Aggregation. Pharmaceutics 2022, 14 (8), 1526. doi:10.3390/pharmaceutics14081526

70. C. Rodríguez Díaz, N. Lafuente-Gómez, C. Coutinho, D. Pardo, H. Alarcón-Iniesta, M. López-Valls, R. Coloma, P. Milán-Rois, M. Domenech, M. Abreu, R. Cantón, J. C. Galán, R. Bocanegra, L. A. Campos, R. Miranda, M. Castellanos and Á. Somoza. Development of colorimetric sensors based on gold nanoparticles for SARS-CoV-2 RdRp, E and S genes detection. Talanta 2022, 243, 123393. doi:10.1016/j.talanta.2022.123393

69. D. García-Soriano, P. Milán-Rois, N. Lafuente-Gómez, C. Navío, L. Gutiérrez, L. Cussó, M. Desco, D. Calle, Á. Somoza and G. Salas. Iron oxide-manganese oxide nanoparticles with tunable morphology and switchable MRI contrast mode triggered by intracellular conditions. Journal of Colloid and Interface Science 2022, 613, 447-460. doi:10.1016/j.jcis.2022.01.070

68. M. López-Valls, C. Escalona-Noguero, C. Rodríguez-Díaz, D. Pardo, M. Castellanos, P. Milán-Rois, C. Martínez-Garay, R. Coloma, M. Abreu, R. Cantón, J. C. Galán, R. Miranda, Á. Somoza and B. Sot. CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles. Analytica Chimica Acta 2022, 1205, 339749. doi:10.1016/j.aca.2022.339749

67. N. Maldonado, A. Latorre, F. Zamora, Á. Somoza, C. J. Gómez-García, A. Bastida and P. Amo-Ochoa. A Nanostructured Cu(II) Coordination Polymer Based on Alanine as a Trifunctional Mimic Enzyme and Efficient Composite in the Detection of Sphingobacteria. Bioinorganic Chemistry and Applications 2022, 2022 (1), 8788221. doi:10.1155/2022/8788221

66. R. del Caño, T. García-Mendiola, D. García-Nieto, R. Álvaro, M. Luna, H. A. Iniesta, R. Coloma, C. R. Diaz, P. Milán-Rois, M. Castellanos, M. Abreu, R. Cantón, J. C. Galán, T. Pineda, F. Pariente, R. Miranda, Á. Somoza and E. Lorenzo. Amplification-free detection of SARS-CoV-2 using gold nanotriangles functionalized with oligonucleotides. Microchimica Acta 2022, 189 (4), 171. doi:10.1007/s00604-022-05272-y

65. P. Milán-Rois, C. Rodriguez-Diaz, M. Castellanos and Á. Somoza. Conjugation of Nucleic Acids and Drugs to Gold Nanoparticles. In: Antisense RNA Design, Delivery, and Analysis. Methods in Molecular Biology, vol. 2434. Springer, 2022, pp. 103-116. doi:10.1007/978-1-0716-2010-6_6

64. N. Lafuente-Gómez, S. Wang, F. Fontana, M. Dhanjani, D. García-Soriano, A. Correia, M. Castellanos, C. Rodriguez Diaz, G. Salas, H. A. Santos and Á. Somoza. Synergistic immunomodulatory effect in macrophages mediated by magnetic nanoparticles modified with miRNAs. Nanoscale 2022, 14 (31), 11129-11138. doi:10.1039/d2nr01767a

2021

63. E. García-Garrido, M. Cordani and Á. Somoza. Modified Gold Nanoparticles to Overcome the Chemoresistance to Gemcitabine in Mutant p53 Cancer Cells. Pharmaceutics 2021, 13 (12), 2067. doi:10.3390/pharmaceutics13122067

62. N. Lafuente-Gómez, P. Milán-Rois, D. García-Soriano, Y. Luengo, M. Cordani, H. Alarcón-Iniesta, G. Salas and Á. Somoza. Smart Modification on Magnetic Nanoparticles Dramatically Enhances Their Therapeutic Properties. Cancers 2021, 13 (16), 4095. doi:10.3390/cancers13164095

61. P. Milán-Rois, A. Quan, F. J. Slack and Á. Somoza. The Role of LncRNAs in Uveal Melanoma. Cancers 2021, 13 (16), 4041. doi:10.3390/cancers13164041

60. C. Battistelli, M. Cordani, M. Diederich, Á. Somoza, S. Valente and R. Strippoli. Editorial: New Approaches to Tackle EMT and Fibrosis: From Epigenetics to Nanotechnology. Frontiers in Pharmacology 2021, 12, 742777. doi:10.3389/fphar.2021.742777

59. V. G. Vegas, A. Latorre, M. L. Marcos, C. J. Gómez-García, Ó. Castillo, F. Zamora, J. Gómez, J. Martínez-Costas, M. Vázquez López, Á. Somoza and P. Amo-Ochoa. Rational Design of Copper(II)–Uracil Nanoprocessed Coordination Polymers to Improve Their Cytotoxic Activity in Biological Media. ACS Applied Materials & Interfaces 2021, 13 (31), 36948-36957. doi:10.1021/acsami.1c11612

58. R. Prajapati and Á. Somoza. Albumin Nanostructures for Nucleic Acid Delivery in Cancer: Current Trend, Emerging Issues, and Possible Solutions. Cancers 2021, 13 (14), 3454. doi:10.3390/cancers13143454

57. A. Latorre, A. Latorre, M. Castellanos, N. Lafuente-Gómez, C. R. Diaz, A. Crespo-Barreda, M. Lecea, M. Cordani, P. Martín-Duque and Á. Somoza. Albumin-based nanostructures for uveal melanoma treatment. Nanomedicine: Nanotechnology, Biology and Medicine 2021, 35, 102391. doi:10.1016/j.nano.2021.102391

56. R. Prajapati, E. Garcia-Garrido and Á. Somoza. Albumin-Based Nanoparticles for the Delivery of Doxorubicin in Breast Cancer. Cancers 2021, 13 (12), 3011. doi:10.3390/cancers13123011

55. M. Cordani, Á. Somoza, M. Tafani, I. Dando and S. Kumar. Editorial: Novel Cancer Treatments Based on Autophagy Modulation. Frontiers in Pharmacology 2021, 12, 650559. doi:10.3389/fphar.2021.650559

54. M. Cordani, E. Resines-Urien, A. Gamonal, P. Milán-Rois, L. Salmon, A. Bousseksou, J. S. Costa and Á. Somoza. Water Soluble Iron-Based Coordination Trimers as Synergistic Adjuvants for Pancreatic Cancer. Antioxidants 2021, 10 (1), 66. doi:10.3390/antiox10010066

53. N. Lafuente-Gómez, A. Latorre, P. Milán-Rois, C. Rodriguez Diaz and Á. Somoza. Stimuli-responsive nanomaterials for cancer treatment: boundaries, opportunities and applications. Chemical Communications 2021, 57 (100), 13662-13677. doi:10.1039/d1cc05056g

2020

52. D. García-Soriano, R. Amaro, N. Lafuente-Gómez, P. Milán-Rois, Á. Somoza, C. Navío, F. Herranz, L. Gutiérrez and G. Salas. The influence of cation incorporation and leaching in the properties of Mn-doped nanoparticles for biomedical applications. Journal of Colloid and Interface Science 2020, 578, 510-521. doi:10.1016/j.jcis.2020.06.011

51. P. Sharma, I. Dando, R. Strippoli, S. Kumar, Á. Somoza, M. Cordani and M. Tafani. Nanomaterials for Autophagy-Related miRNA-34a Delivery in Cancer Treatment. Frontiers in Pharmacology 2020, 11, 1141. doi:10.3389/fphar.2020.01141

50. A. Lazaro-Carrillo, M. Calero, A. Aires, A. L. Cortajarena, B. M. Simões, A. Latorre, Á. Somoza, R. B. Clarke, R. Miranda and A. Villanueva. Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells. Cancers 2020, 12 (6), 1397. doi:10.3390/cancers12061397

49. S. Piehler, H. Dähring, J. Grandke, J. Göring, P. Couleaud, A. Aires, A. L. Cortajarena, J. Courty, A. Latorre, Á. Somoza, U. Teichgräber and I. Hilger. Iron Oxide Nanoparticles as Carriers for DOX and Magnetic Hyperthermia after Intratumoral Application into Breast Cancer in Mice: Impact and Future Perspectives. Nanomaterials 2020, 10 (6), 1016. doi:10.3390/nano10061016

48. T. Rigotti, J. Asenjo‐Pascual, A. Martín‐Somer, P. Milán Rois, M. Cordani, S. Díaz‐Tendero, Á. Somoza, A. Fraile and J. Alemán. Boron Dipyrromethene (BODIPY) as Electron‐Withdrawing Group in Asymmetric Copper‐Catalyzed [3+2] Cycloadditions for the Synthesis of Pyrrolidine‐Based Biological Sensors. Advanced Synthesis & Catalysis 2020, 362 (6), 1345-1355. doi:10.1002/adsc.201901465

47. S. Romero-Pérez, I. López-Martín, M. C. Martos-Maldonado, Á. Somoza and D. González-Rodríguez. Synthesis of Phosphoramidite Monomers Equipped with Complementary Bases for Solid-Phase DNA Oligomerization. Organic Letters 2020, 22 (1), 41-45. doi:10.1021/acs.orglett.9b03801

46. M. Cordani, R. Strippoli and Á. Somoza. Nanomaterials as Inhibitors of Epithelial Mesenchymal Transition in Cancer Treatment. Cancers 2020, 12 (1), 25. doi:10.3390/cancers12010025

2019

45. M. Sanhaji, J. Göring, P. Couleaud, A. Aires, A. L. Cortajarena, J. Courty, A. Prina-Mello, M. Stapf, R. Ludwig, Y. Volkov, A. Latorre, Á. Somoza, R. Miranda and I. Hilger. The phenotype of target pancreatic cancer cells influences cell death by magnetic hyperthermia with nanoparticles carrying gemicitabine and the pseudo-peptide NucAnt. Nanomedicine: Nanotechnology, Biology and Medicine 2019, 20, 101983. doi:10.1016/j.nano.2018.12.019

44. A. Latorre, A. Latorre, M. Castellanos, C. Rodriguez Diaz, A. Lazaro-Carrillo, T. Aguado, M. Lecea, S. Romero-Pérez, M. Calero, J. M. Sanchez-Puelles, Á. Villanueva and Á. Somoza. Multifunctional Albumin-Stabilized Gold Nanoclusters for the Reduction of Cancer Stem Cells. Cancers 2019, 11 (7), 969. doi:10.3390/cancers11070969

43. M. Cordani and Á. Somoza. Targeting autophagy using metallic nanoparticles: a promising strategy for cancer treatment. Cellular and Molecular Life Sciences 2019, 76 (7), 1215-1242. doi:10.1007/s00018-018-2973-y

42. C. Coutinho and Á. Somoza. MicroRNA sensors based on gold nanoparticles. Analytical and Bioanalytical Chemistry 2019, 411 (9), 1807-1824. doi:10.1007/s00216-018-1450-7

2018

41. T. Naranjo, K. M. Lemishko, S. de Lorenzo, Á. Somoza, F. Ritort, E. M. Pérez and B. Ibarra. Dynamics of individual molecular shuttles under mechanical force. Nature Communications 2018, 9 (1), 4512. doi:10.1038/s41467-018-06905-8

40. P. Milán Rois, A. Latorre, C. Rodriguez Diaz, Á. Del Moral and Á. Somoza. Reprogramming Cells for Synergistic Combination Therapy with Nanotherapeutics against Uveal Melanoma. Biomimetics 2018, 3 (4), 28. doi:10.3390/biomimetics3040028

39. D. Bouzada, I. Salvadó, G. Barka, G. Rama, J. Martínez-Costas, R. Lorca, Á. Somoza, M. Melle-Franco, M. E. Vázquez and M. Vázquez López. Selective G-quadruplex binding by oligoarginine-Ru(dppz) metallopeptides. Chemical Communications 2018, 54 (6), 658-661. doi:10.1039/c7cc08286j

38. S. Royuela, E. García-Garrido, M. Martín Arroyo, M. J. Mancheño, M. M. Ramos, D. González-Rodríguez, Á. Somoza, F. Zamora and J. L. Segura. Uracil grafted imine-based covalent organic framework for nucleobase recognition. Chemical Communications 2018, 54 (63), 8729-8732. doi:10.1039/c8cc04346a

2017

37. B. Álvarez‐Rodríguez, A. Latorre, C. Posch and Á. Somoza. Recent advances in uveal melanoma treatment. Medicinal Research Reviews 2017, 37 (6), 1350-1372. doi:10.1002/med.21460

36. D. Mendez-Gonzalez, M. Laurenti, A. Latorre, Á. Somoza, A. Vazquez, A. I. Negredo, E. López-Cabarcos, O. G. Calderón, S. Melle and J. Rubio-Retama. Oligonucleotide Sensor Based on Selective Capture of Upconversion Nanoparticles Triggered by Target-Induced DNA Interstrand Ligand Reaction. ACS Applied Materials & Interfaces 2017, 9 (14), 12272-12281. doi:10.1021/acsami.7b00575

35. T. Naranjo, F. Cerrón, B. Nieto-Ortega, A. Latorre, Á. Somoza, B. Ibarra and E. M. Pérez. Mechanical measurement of hydrogen bonded host–guest systems under non-equilibrium, near-physiological conditions. Chemical Science 2017, 8 (9), 6037-6041. doi:10.1039/c7sc03044d

34. V. G. Vegas, R. Lorca, A. Latorre, K. Hassanein, C. J. Gómez‐García, O. Castillo, Á. Somoza, F. Zamora and P. Amo‐Ochoa. Copper(II)–Thymine Coordination Polymer Nanoribbons as Potential Oligonucleotide Nanocarriers. Angewandte Chemie International Edition 2017, 56 (4), 987-991. doi:10.1002/anie.201609031

2016

33. S. Javani, R. Lorca, A. Latorre, C. Flors, A. L. Cortajarena and Á. Somoza. Antibacterial Activity of DNA-Stabilized Silver Nanoclusters Tuned by Oligonucleotide Sequence. ACS Applied Materials & Interfaces 2016, 8 (16), 10147-10154. doi:10.1021/acsami.6b00670

32. A. Latorre, A. Latorre and Á. Somoza. Modified RNAs in CRISPR/Cas9: An Old Trick Works Again. Angewandte Chemie International Edition 2016, 55 (11), 3548-3550. doi:10.1002/anie.201512002

31. A. Aires, S. M. Ocampo, B. M. Simões, M. Josefa Rodríguez, J. F. Cadenas, P. Couleaud, K. Spence, A. Latorre, R. Miranda, Á. Somoza, R. B. Clarke, J. L. Carrascosa and A. L. Cortajarena. Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells. Nanotechnology 2016, 27 (6), 065103. doi:10.1088/0957-4484/27/6/065103

2015

30. M. Tintoré, S. Mazzini, L. Polito, M. Marelli, A. Latorre, Á. Somoza, A. Aviñó, C. Fàbrega and R. Eritja. Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers. International Journal of Molecular Sciences 2015, 16 (11), 27625-27639. doi:10.3390/ijms161126046

29. P. Couleaud, S. Adan-Bermudez, A. Aires, S. H. Mejías, B. Sot, Á. Somoza and A. L. Cortajarena. Designed Modular Proteins as Scaffolds To Stabilize Fluorescent Nanoclusters. Biomacromolecules 2015, 16 (12), 3836-3844. doi:10.1021/acs.biomac.5b01147

28. S. Kossatz, J. Grandke, P. Couleaud, A. Latorre, A. Aires, K. Crosbie-Staunton, R. Ludwig, H. Dähring, V. Ettelt, A. Lazaro-Carrillo, M. Calero, M. Sader, J. Courty, Y. Volkov, A. Prina-Mello, A. Villanueva, Á. Somoza, A. L. Cortajarena, R. Miranda and I. Hilger. Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery. Breast Cancer Research 2015, 17 (1), 66. doi:10.1186/s13058-015-0576-1

27. C. Posch, A. Latorre, M. B. Crosby, A. Celli, A. Latorre, I. Vujic, M. Sanlorenzo, G. A. Green, J. Weier, M. Zekhtser, J. Ma, G. Monico, D. H. Char, D. Jusufbegovic, K. Rappersberger, Á. Somoza and S. Ortiz-Urda. Detection of GNAQ mutations and reduction of cell viability in uveal melanoma cells with functionalized gold nanoparticles. Biomedical Microdevices 2015, 17 (1), 15. doi:10.1007/s10544-014-9908-7

2014

26. A. Latorre and Á. Somoza. Oligonucleotide‐Stabilized Silver Nanoclusters. In: DNA in Supramolecular Chemistry and Nanotechnology. Wiley, 2014, pp. 308-327. doi:10.1002/9781118696880.ch4.4

25. A. Latorre and Á. Somoza. Glutathione-Triggered Drug Release from Nanostructures. Current Topics in Medicinal Chemistry 2014, 14 (23), 2662-2671. doi:10.2174/1568026614666141215143659

24. A. Latorre, P. Couleaud, A. Aires, A. L. Cortajarena and Á. Somoza. Multifunctionalization of magnetic nanoparticles for controlled drug release: A general approach. European Journal of Medicinal Chemistry 2014, 82, 355-362. doi:10.1016/j.ejmech.2014.05.078

23. M. Garavís, B. López-Méndez, Á. Somoza, J. Oyarzabal, C. Dalvit, A. Villasante, R. Campos-Olivas and C. González. Discovery of Selective Ligands for Telomeric RNA G-quadruplexes (TERRA) through 19F-NMR Based Fragment Screening. ACS Chemical Biology 2014, 9 (7), 1559-1566. doi:10.1021/cb500100z

22. A. Latorre, C. Posch, Y. Garcimartín, S. Ortiz-Urda and Á. Somoza. Single-point mutation detection in RNA extracts using gold nanoparticles modified with hydrophobic molecular beacon-like structures. Chemical Communications 2014, 50 (23), 3018-3020. doi:10.1039/c3cc47862a

21. A. Latorre, C. Posch, Y. Garcimartín, A. Celli, M. Sanlorenzo, I. Vujic, J. Ma, M. Zekhtser, K. Rappersberger, S. Ortiz-Urda and Á. Somoza. DNA and aptamer stabilized gold nanoparticles for targeted delivery of anticancer therapeutics. Nanoscale 2014, 6 (13), 7436-7442. doi:10.1039/c4nr00019f

2013

20. S. Pérez-Rentero, Á. Somoza, S. Grijalvo, J. Janoušek, M. Bělohradský, I. G. Stará, I. Starý and R. Eritja. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions. Journal of Chemistry 2013, 2013 (1), 650610. doi:10.1155/2013/650610

19. A. Latorre, R. Lorca and Á. Somoza. Fluorescent DNA Stabilized Silver Nanoclusters as Biosensors. Journal of Chemistry 2013, 2013 (1), 631421. doi:10.1155/2013/631421

18. A. Latorre, R. Lorca, F. Zamora and Á. Somoza. Enhanced fluorescence of silver nanoclusters stabilized with branched oligonucleotides. Chemical Communications 2013, 49 (43), 4950-4952. doi:10.1039/c3cc40446c

2012

17. L. I. Cabrera, Á. Somoza, J. F. Marco, C. J. Serna and M. Puerto Morales. Synthesis and surface modification of uniform MFe2O4 (M = Fe, Mn, and Co) nanoparticles with tunable sizes and functionalities. Journal of Nanoparticle Research 2012, 14 (6), 873. doi:10.1007/s11051-012-0873-x

16. A. Latorre and Á. Somoza. DNA‐Mediated Silver Nanoclusters: Synthesis, Properties and Applications. ChemBioChem 2012, 13 (7), 951-958. doi:10.1002/cbic.201200053

15. S. Pérez-Rentero, I. Gállego, Á. Somoza, R. Ferreira, J. Janoušek, M. Bělohradský, I. G. Stará, I. Starý and R. Eritja. Interstrand interactions on DNA duplexes modified by TTF units at the 3′ or 5′-ends. RSC Advances 2012, 2 (10), 4069-4071. doi:10.1039/c2ra20477k

2011

14. Á. Somoza. RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development. Edited by Paul H. Johnson. ChemMedChem 2011, 6 (7), 1311-1312. doi:10.1002/cmdc.201100167

2010

13. Á. Somoza. Modificaciones Químicas en ARN interferente: De la investigación básica a las aplicaciones terapéuticas. Anales de Química 2010, 106 (3), 215. Link to article

12. Á. Somoza, M. Terrazas and R. Eritja. Modified siRNAs for the study of the PAZ domain. Chemical Communications 2010, 46 (24), 4270-4272. doi:10.1039/c003221b

11. L. I. Cabrera, Á. Somoza, C. J. Serna, M. P. Morales and E. Borsella. Synthesis of MFe2O4 (M = Fe, Mn) Nanoparticles with Tunable Sizes. AIP Conference Proceedings 2010, 1275, 13-16. doi:10.1063/1.3505063

2009

10. Á. Somoza. Evolution of DNA Origami. Angewandte Chemie International Edition 2009, 48 (50), 9406-9408. doi:10.1002/anie.200904802

2008

9. Á. Somoza, A. P. Silverman, R. M. Miller, J. Chelliserrykattil and E. T. Kool. Steric Effects in RNA Interference: Probing the Influence of Nucleobase Size and Shape. Chemistry – A European Journal 2008, 14 (26), 7978-7987. doi:10.1002/chem.200800837

8. Á. Somoza. Protecting groups for RNA synthesis: an increasing need for selective preparative methods. Chemical Society Reviews 2008, 37 (12), 2668-2675. doi:10.1039/b809851d

2007

7. M. C. Carreño, E. Merino, M. Ribagorda, Á. Somoza and A. Urbano. Enantioselective Synthesis of Natural Polyoxygenated Cyclohexanes and Cyclohexenes from [(p‐Tolylsulfinyl)methyl]‐p‐quinols. Chemistry – A European Journal 2007, 13 (4), 1064-1077. doi:10.1002/chem.200601330

6. M. C. Carreño, Á. Somoza, M. Ribagorda and A. Urbano. Asymmetric Synthesis of Rubiginones A2 and C2 and Their 11‐Methoxy Regioisomers. Chemistry – A European Journal 2007, 13 (3), 879-890. doi:10.1002/chem.200600809

2006

5. Á. Somoza, J. Chelliserrykattil and E. T. Kool. The Roles of Hydrogen Bonding and Sterics in RNA Interference. Angewandte Chemie International Edition 2006, 45 (30), 4994-4997. doi:10.1002/anie.200601311

2005

4. M. C. Carreño, E. Merino, M. Ribagorda, Á. Somoza and A. Urbano. Enantioselective Synthesis of (+)- and (−)-Dihydroepiepoformin and (+)-Epiepoformin. Organic Letters 2005, 7 (7), 1419-1422. doi:10.1021/ol050287a

2003

3. A. Almorín, M. C. Carreño, Á. Somoza and A. Urbano. Diastereodivergent additions of aluminum and magnesium reagents to [(S)S]-3,6-dimethoxy-2-(p-tolylsulfinyl)-benzaldehyde. Tetrahedron Letters 2003, 44 (30), 5597-5600. doi:10.1016/s0040-4039(03)01369-8

2002

2. M. C. Carreño, M. Ribagorda, Á. Somoza and A. Urbano. Enantioselective Total Synthesis of Angucyclinone-Type Antibiotics Rubiginones A2 and C2. Angewandte Chemie International Edition 2002, 41 (15), 2755-2757. doi:10.1002/1521-3773(20020802)41:15<2755::AID-ANIE2755>3.0.CO;2-A

1. M. C. Carreño, M. Pérez-González, M. Ribagorda, Á. Somoza and A. Urbano. β-Hydroxysulfoxides as chiral cyclic ketone equivalents: enantioselective synthesis of polysubstituted cyclohexanones, cyclohexenones and cyclohexenediones. Chemical Communications 2002 (24), 3052-3053. doi:10.1039/b209121f