The NanoBiotechnology Group is mainly focused on the use of bioactive molecules and nanoparticles in nanomedicine & nanotechnology. It possesses a multidisciplinary philosophy, and it is led by Dr. Alvaro Somoza, an expert in the use of modified oligonucleotides and nanostructures in nanomedicine. The group deals with several research lines, centered on the use of modified oligonucleotides and proteins to create new nanomedical tools and sensors.
– Nanoparticles in Drug Delivery, using different nanostructures to deliver different drugs and nucleic acids for the treatment of different diseases.
– The design of new strategies for efficient editing of Uveal Melanoma and Pancreatic cancer cell lines based on the delivery ofthe CRISPR system.
– Nanosensors for multiples diseases, such as Uveal, Melanoma, Pancreatic cancer or Duchenne Muscular Dystrophy.
– Modified magnetic nanoparticles for the treatment of pancreatic cancer. (NoCanTher project)
Funded Projects
Active Projects
Red Madrileña de Nanomedicina en Imagen Molecular (RENIM) (S2022/BMD-7403 RENIM-CM. Funding Agency: Comunidad de Madrid. PI IMDEA Nanociencia: Álvaro Somoza. Coordinator: Manuel Desco
Reactivation of anti-tumor immune cell responses by functionalized nanoparticles in melanoma. Funding Agency: Fundación Científica AECC. PI IMDEA Nanociencia: Álvaro Somoza. Coordinator: Héctor Peinado
Functionalized nanoparticles for targeted genome editing in Duchenne Muscular Dystrophy. Funding Agency: AFM-Telethon. PI IMDEA Nanociencia: Álvaro Somoza. Coordinator: Daniela Palacios
Herramientas nanobiotecnológicas para detección y tratamiento de enfermedades raras: cáncer pancreático, melanoma de úvea y distrofia muscular de Duchenne (NanoRare) ( PID2020-119352RB-I00). Funding Agency: Ministerio de Ciencia e Innovación. Pis: Álvaro Somoza & Begoña Sot.
Desarrollo de un sensor basado en nanopartículas de oro para el diagnóstico del Virus de Papiloma Humano (SENSOR-DOC)( IND2020/IND-17517). Funding Agency: Comunidad de Madrid. PI IMDEA Nanociencia: Álvaro Somoza
Previous projects
Funding agency: Asociación Española Contra el CáncerNanomedicine Upscaling for Early
Funding agency: European Commission , H2020, REF: GA 685795
WEB: NoCanTher
Funding agency: EuronanoMed II (MINECO). REF: PCIN-2016-167
WEB: NanoMir
Funding agency: MINECO, REF: SAF2014-56763-R
