Milagros Castellanos

IMG_20181024_123840_HDR

PUBLICATIONS

Milagros Castellanos, Nivin Mothic, and Victor Muñoz.  Eukaryotic transcription factors can track and control their target genes using DNA antennas. Nat. Comm. 2019 (Resubmitted with minor revisions). Live status of the paper at 17/10/2019.

 

Ana Latorre, Alfonso Latorre, Milagros Castellanos, Ciro Rodriguez Diaz, Ana Lazaro-Carrillo, Tania Aguado, Mercedes Lecea, Sonia Romero-Pérez, Macarena Calero, José María Sanchez-Puelles*, Ángeles Villanueva * and Álvaro Somoza*. Multifunctional Albumin-Stabilized Gold Nanoclusters for the Reduction of Cancer Stem Cells. Cancers. 2019. 11: 969.

 

Javier Conesa-Egea, Alberto Moreno-Vázquez, Vanesa Fernández-Moreira, Yolanda Ballesteros, Milagros Castellanos, Félix Zamora and Pilar Amo-Ochoa*. Micro and Nano Smart Composite Films Based on Copper-Iodine Coordination Polymer as Thermochromic Biocompatible Sensors. Polymers. 2019. 11: 1047.

 

Castellanos M, Torres-Pardo A, Rodríguez-Pérez R, Gasset M. Amyloid assembly endows Gad m1 with biomineralization properties. Biomolecules. 2018. 8(1).pii E13.

 

Sánchez R, Martínez J, Montoya L, Castellanos M and Gasset M. Mapping amyloid regions in Gad m 1 chain with peptide arrays. Methods Mol. Biol.: Amyloid Proteins: Methods and Protocols, Third Edition. 2018; 1779:197-207.

 

Carrillo PJP, Medrano M, Valbuena A, Rodríguez-Huete A, Castellanos M, Pérez R and Mateu MG. Amino acid side chains buried along intersubunit interfaces in a viral capsid preserve low mechanical stiffness associated to virus infectivity. ACS Nano. 2017 Feb 28; 11(2):2194-2208.

 

Guerra P, Valbuena A, Querol J, Silva C, Castellanos M, Rodríguez-Huete A, Garriga D, Mateu MG and Verdaguer N. Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations. Sci. Rep. 2017. Jun 22; 7(1):4101.

 

Castellanos M, Muñoz V. Beyond diffusion-controlled kinetics: How a protein implements a fast search on DNA to get to its specific binding site. Biophys. J. 2017. Supplement, 518a.

 

Castellanos M, Carrillo PJP and Mateu MG. Quantitatively probing propensity for structural transitions in engineered virus nanoparticles by single-molecule mechanical analysis. Nanoscale. 2015. 7, 5654.

 

Martínez J, Sánchez R, Milagros Castellanos, Fernández-Escamilla AM, Vázquez-Cortés S, Fernández-Rivas M and Gasset M. Fish beta-parvalbumin acquires allergenic properties by amyloid assembly. Swiss Medical Weekly. 2015. 145:w14128 – smw.2015.14128.

 

Martínez J, Sánchez R, Milagros Castellanos, Makarava N, Aguzzi A, Baskakov IV and Gasset M. PrP charge structure encodes interdomain interactions. Sci. Rep. 2015. 5:13623.

 

Castellanos M, Pérez R, Rodríguez-Huete A, Grueso E, Almendral JM and Mateu MG. A slender tract of glycines is required for translocation of protein VP2 N-terminal domain through the parvovirus MVM capsid channel to initiate infection. Biochem. J. 2013. 455 – 1, 87 – 94.

 

Castellanos M*, Pérez R*, Carrasco C, Hernando-Pérez M, Gómez-Herrero J, de Pablo PJ and Mateu MG. Mechanical Elasticity as a Physical Signature of Conformational Dynamics in a Virus Particle. PNAS. 2012. 109 – 30, 12028 – 12033. *equally contributed.

 

Castellanos M, Pérez R, Carrillo PJP, de Pablo PJ and Mateu MG. Mechanical disassembly of single virus particles reveals kinetic intermediates predicted by theory. Biophys. J. 2012. 102 – 11, 2615 – 2624.

Pérez R, Castellanos M, Rodríguez-Huete A and Mateu MG. Molecular determinants of self-association and rearrangement of a trimeric intermediate during the assembly of a parvovirus capsid. JMB. 2011. 413 – 1, 32 – 40.

 

Alonso-C LM, Trinidad EM, de Garcillán B, Ballesteros M, Castellanos M, Cotillo I, Muñoz JJ and Zapata AG. Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cell. Leuk Res. 2009. 33(3):395-406.

 

Carrasco C, Hernando-Pérez M, Pascual E, Castellanos M, Carrascosa JL, Mateu MG and de Pablo PJ. Single Particle Force Spectroscopy Reveals Virus DNA Storage Strategies And Structural Properties Of Capsids And Virions. Biophys. J. 2009. 96 – 3, Supplement 1, 421a.

 

Carrasco C, Douas M, Miranda R, Castellanos M, Serena PA, Carascosa JL, Mateu MG, Marqués M and de Pablo PJ. The capillarity of nanometric water menisci confined inside closed-geometry viral cages. PNAS. 2009 106 – 14, 5475 – 5780.

 

Serena PA, Douas M, Marqués M, Carrasco C, de Pablo PJ, Miranda R, Carascosa JL, Castellanos M and Mateu MG. MC simulations of water meniscus in nanocontainers: explaining the collapse of viral particles due to capillary forces. Phys. Status Solidi. 2009. C 6 – 10, 2128 – 2132.

 

Carrasco C*, Castellanos M*; de Pablo PJ and Mateu MG. Manipulation of the mechanical properties of a virus by protein engineering. PNAS. 2008 Mar 18; 105(11):4150-5. *equally contributed.